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Alpha Radiation as a Way to Target Heterochromatic and Gamma Radiation-Exposed Breast Cancer Cells

Compact chromatin is linked to a poor tumour prognosis and resistance to radiotherapy from photons. We investigated DNA damage induction and repair in the context of chromatin structure for densely ionising alpha radiation as well as its therapeutic potential. Chromatin opening by histone deacetylas...

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Detalles Bibliográficos
Autores principales: Svetličič, Maja, Bomhard, Anton, Sterr, Christoph, Brückner, Fabian, Płódowska, Magdalena, Lisowska, Halina, Lundholm, Lovisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291130/
https://www.ncbi.nlm.nih.gov/pubmed/32397212
http://dx.doi.org/10.3390/cells9051165