Cargando…
Alpha Radiation as a Way to Target Heterochromatic and Gamma Radiation-Exposed Breast Cancer Cells
Compact chromatin is linked to a poor tumour prognosis and resistance to radiotherapy from photons. We investigated DNA damage induction and repair in the context of chromatin structure for densely ionising alpha radiation as well as its therapeutic potential. Chromatin opening by histone deacetylas...
Autores principales: | Svetličič, Maja, Bomhard, Anton, Sterr, Christoph, Brückner, Fabian, Płódowska, Magdalena, Lisowska, Halina, Lundholm, Lovisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291130/ https://www.ncbi.nlm.nih.gov/pubmed/32397212 http://dx.doi.org/10.3390/cells9051165 |
Ejemplares similares
-
Biological effectiveness of very high gamma dose rate and its implication for radiological protection
por: Olofsson, Dante, et al.
Publicado: (2020) -
Hypothermia differentially modulates the formation and decay of NBS1, γH2AX and 53BP1 foci in U2OS cells exposed to gamma radiation
por: Płódowska, Magdalena, et al.
Publicado: (2022) -
The order of sequential exposure of U2OS cells to gamma and alpha radiation influences the formation and decay dynamics of NBS1 foci
por: Tartas, Adrianna, et al.
Publicado: (2023) -
Impact of ATM and DNA-PK Inhibition on Gene Expression and Individual Response of Human Lymphocytes to Mixed Beams of Alpha Particles and X-Rays
por: Cheng, Lei, et al.
Publicado: (2019) -
The DNA damage response to radiological imaging: from ROS and γH2AX foci induction to gene expression responses in vivo
por: López-Riego, Milagrosa, et al.
Publicado: (2023)