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Analysis of Motor Neurons Differentiated from Human Induced Pluripotent Stem Cells for the Use in Cell-Based Botulinum Neurotoxin Activity Assays

Botulinum neurotoxins (BoNTs) are potent neurotoxins produced by bacteria, which inhibit neurotransmitter release, specifically in their physiological target known as motor neurons (MNs). For the potency assessment of BoNTs produced for treatment in traditional and aesthetic medicine, the mouse leth...

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Detalles Bibliográficos
Autores principales: Schenke, Maren, Schjeide, Brit-Maren, Püschel, Gerhard P., Seeger, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291138/
https://www.ncbi.nlm.nih.gov/pubmed/32344847
http://dx.doi.org/10.3390/toxins12050276