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Clostridium perfringens Epsilon-Toxin Impairs the Barrier Function in MDCK Cell Monolayers in a Ca(2+)-Dependent Manner

Epsilon-toxin produced by Clostridium perfringens significantly contributes to the pathogeneses of enterotoxemia in ruminants and multiple sclerosis in humans. Epsilon-toxin forms a heptameric oligomer in the host cell membrane, promoting cell disruption. Here, we investigate the effect of epsilon-t...

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Detalles Bibliográficos
Autores principales: Nagahama, Masahiro, Seike, Soshi, Ochi, Sadayuki, Kobayashi, Keiko, Takehara, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291203/
https://www.ncbi.nlm.nih.gov/pubmed/32365779
http://dx.doi.org/10.3390/toxins12050286