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Clostridium perfringens Epsilon-Toxin Impairs the Barrier Function in MDCK Cell Monolayers in a Ca(2+)-Dependent Manner
Epsilon-toxin produced by Clostridium perfringens significantly contributes to the pathogeneses of enterotoxemia in ruminants and multiple sclerosis in humans. Epsilon-toxin forms a heptameric oligomer in the host cell membrane, promoting cell disruption. Here, we investigate the effect of epsilon-t...
Autores principales: | Nagahama, Masahiro, Seike, Soshi, Ochi, Sadayuki, Kobayashi, Keiko, Takehara, Masaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291203/ https://www.ncbi.nlm.nih.gov/pubmed/32365779 http://dx.doi.org/10.3390/toxins12050286 |
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