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Inhibition of Anti-Apoptotic Bcl-2 Proteins in Preclinical and Clinical Studies: Current Overview in Cancer

The dynamic interplay between pro-death and pro-survival Bcl-2 family proteins is responsible for a cell’s fate. Due to the recognized relevance of this family in cancer progression and response to therapy, different efforts have made in recent years in order to develop small molecules able to targe...

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Detalles Bibliográficos
Autores principales: D’Aguanno, Simona, Del Bufalo, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291206/
https://www.ncbi.nlm.nih.gov/pubmed/32455818
http://dx.doi.org/10.3390/cells9051287