Multi-Stress Induction of the Mycobacterium tuberculosis MbcTA Bactericidal Toxin-Antitoxin System

MbcTA is a type II toxin/antitoxin (TA) system of Mycobacterium tuberculosis. The MbcT toxin triggers mycobacterial cell death in vitro and in vivo through the phosphorolysis of the essential metabolite NAD(+) and its bactericidal activity is neutralized by physical interaction with its cognate anti...

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Detalles Bibliográficos
Autores principales: Ariyachaokun, Kanchiyaphat, Grabowska, Anna D., Gutierrez, Claude, Neyrolles, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291234/
https://www.ncbi.nlm.nih.gov/pubmed/32429486
http://dx.doi.org/10.3390/toxins12050329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291234/
https://www.ncbi.nlm.nih.gov/pubmed/32429486
http://dx.doi.org/10.3390/toxins12050329

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