Yeast-Based Genetic Interaction Analysis of Human Kinome

Kinases are critical intracellular signaling proteins. To better understand kinase-mediated signal transduction, a large-scale human–yeast genetic interaction screen was performed. Among 597 human kinase genes tested, 28 displayed strong toxicity in yeast when overexpressed. En masse transformation...

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Detalles Bibliográficos
Autores principales: Kim, Jae-Hong, Seo, Yeojin, Jo, Myungjin, Jeon, Hyejin, Lee, Won-Ha, Yachie, Nozomu, Zhong, Quan, Vidal, Marc, Roth, Frederick P., Suk, Kyoungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291280/
https://www.ncbi.nlm.nih.gov/pubmed/32392905
http://dx.doi.org/10.3390/cells9051156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291280/
https://www.ncbi.nlm.nih.gov/pubmed/32392905
http://dx.doi.org/10.3390/cells9051156

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