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Dynamic Characterization of Structural, Molecular, and Electrophysiological Phenotypes of Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids, and Comparison with Fetal and Adult Gene Profiles

Background: The development of 3D cerebral organoid technology using human-induced pluripotent stem cells (iPSCs) provides a promising platform to study how brain diseases are appropriately modeled and treated. So far, understanding of the characteristics of organoids is still in its infancy. The cu...

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Detalles Bibliográficos
Autores principales: Logan, Sarah, Arzua, Thiago, Yan, Yasheng, Jiang, Congshan, Liu, Xiaojie, Yu, Lai-Kang, Liu, Qing-Song, Bai, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291286/
https://www.ncbi.nlm.nih.gov/pubmed/32456176
http://dx.doi.org/10.3390/cells9051301