Measuring Alphavirus Fidelity Using Non-Infectious Virus Particles

Mutations are incorporated into the genomes of RNA viruses at an optimal frequency and altering this precise frequency has been proposed as a strategy to create live-attenuated vaccines. However, determining the effect of specific mutations that alter fidelity has been difficult because of the rapid...

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Detalles Bibliográficos
Autores principales: Patterson, Edward I., Khanipov, Kamil, Swetnam, Daniele M., Walsdorf, Samantha, Kautz, Tiffany F., Thangamani, Saravanan, Fofanov, Yuriy, Forrester, Naomi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291308/
https://www.ncbi.nlm.nih.gov/pubmed/32429270
http://dx.doi.org/10.3390/v12050546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291308/
https://www.ncbi.nlm.nih.gov/pubmed/32429270
http://dx.doi.org/10.3390/v12050546

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