Insightful Backbone Modifications Preventing Proteolytic Degradation of Neurotensin Analogs Improve NTS1-Induced Protective Hypothermia

Therapeutic hypothermia represents a brain-protective strategy for multiple emergency situations, such as stroke or traumatic injury. Neurotensin (NT), which exerts its effects through activation of two G protein-coupled receptors, namely NTS1 and NTS2, induces a strong and long-lasting decrease in...

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Detalles Bibliográficos
Autores principales: Previti, Santo, Vivancos, Mélanie, Rémond, Emmanuelle, Beaulieu, Sabrina, Longpré, Jean-Michel, Ballet, Steven, Sarret, Philippe, Cavelier, Florine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291367/
https://www.ncbi.nlm.nih.gov/pubmed/32582624
http://dx.doi.org/10.3389/fchem.2020.00406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291367/
https://www.ncbi.nlm.nih.gov/pubmed/32582624
http://dx.doi.org/10.3389/fchem.2020.00406

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