Influenza a virus antagonizes type I and type II interferon responses via SOCS1-dependent ubiquitination and degradation of JAK1

BACKGROUND: Although influenza A virus (IAV) employs diverse strategies to evade IFN responses by inhibiting the synthesis of IFN, how IAV regulates signaling downstream of IFN is incompletely understood. METHODS: In this study, we used Western blot-based protein analysis coupled with RT-qPCR, overe...

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Detalles Bibliográficos
Autores principales: Du, Yinping, Yang, Fan, Wang, Qiuxia, Xu, Nuo, Xie, Yizhang, Chen, Sujuan, Qin, Tao, Peng, Daxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291424/
https://www.ncbi.nlm.nih.gov/pubmed/32532301
http://dx.doi.org/10.1186/s12985-020-01348-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291424/
https://www.ncbi.nlm.nih.gov/pubmed/32532301
http://dx.doi.org/10.1186/s12985-020-01348-4

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