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Influenza a virus antagonizes type I and type II interferon responses via SOCS1-dependent ubiquitination and degradation of JAK1

BACKGROUND: Although influenza A virus (IAV) employs diverse strategies to evade IFN responses by inhibiting the synthesis of IFN, how IAV regulates signaling downstream of IFN is incompletely understood. METHODS: In this study, we used Western blot-based protein analysis coupled with RT-qPCR, overe...

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Detalles Bibliográficos
Autores principales:	Du, Yinping, Yang, Fan, Wang, Qiuxia, Xu, Nuo, Xie, Yizhang, Chen, Sujuan, Qin, Tao, Peng, Daxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291424/ https://www.ncbi.nlm.nih.gov/pubmed/32532301 http://dx.doi.org/10.1186/s12985-020-01348-4

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