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Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis

BACKGROUND: The Chinese herbal compound Heshouwuyin has been shown to downregulate the apoptotic rate of testicular tissue cells in Wistar naturally aging rats, and this effect might be related to the mitochondrial pathway [15]. Apoptotic protease activating factor-1 (Apaf-1) is a major component of...

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Detalles Bibliográficos
Autores principales: Wang, Hongjie, Zhu, Juan, Jiang, Liping, Shan, Boying, Xiao, Peihan, Ai, Jiayi, Li, Na, Qi, Feng, Niu, Siyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291440/
https://www.ncbi.nlm.nih.gov/pubmed/32527252
http://dx.doi.org/10.1186/s12906-020-02904-9