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CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats

BACKGROUND: Inflammation is a common pathophysiological trait found in both hypertension and cardiac vascular disease. Recent evidence indicates that fractalkine (FKN) and its receptor CX3CR1 have been linked to inflammatory response in the brain of hypertensive animal models. Here, we investigated...

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Detalles Bibliográficos
Autores principales: Ho, Chiu-Yi, Lin, Yu-Te, Chen, Hsin-Hung, Ho, Wen-Yu, Sun, Gwo-Ching, Hsiao, Michael, Lu, Pei-Jung, Cheng, Pei-Wen, Tseng, Ching-Jiunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291459/
https://www.ncbi.nlm.nih.gov/pubmed/32532282
http://dx.doi.org/10.1186/s12974-020-01857-7