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Neuronal aldosterone elicits a distinct genomic response in pain signaling molecules contributing to inflammatory pain
BACKGROUND: Recently, mineralocorticoid receptors (MR) were identified in peripheral nociceptive neurons, and their acute antagonism was responsible for immediate and short-lasting (non-genomic) antinociceptive effects. The same neurons were shown to produce the endogenous ligand aldosterone by the...
Autores principales: | Shaqura, Mohammed, Li, Li, Mohamed, Doaa M., Li, Xiongjuan, Treskatsch, Sascha, Buhrmann, Constanze, Shakibaei, Mehdi, Beyer, Antje, Mousa, Shaaban A., Schäfer, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291517/ https://www.ncbi.nlm.nih.gov/pubmed/32532285 http://dx.doi.org/10.1186/s12974-020-01864-8 |
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