Effects of concomitant use of prasugrel with edoxaban on bleeding time, pharmacodynamics, and pharmacokinetics of edoxaban in healthy elderly Japanese male subjects: a clinical pharmacology study

BACKGROUND: Dual therapy with a direct oral anticoagulant (DOAC) plus a P2Y(12) receptor inhibitor is recommended in patients with nonvalvular atrial fibrillation who undergo percutaneous coronary intervention. Thus, we evaluated the effects of DOAC edoxaban plus P2Y(12) receptor inhibitor prasugrel...

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Detalles Bibliográficos
Autores principales: Ikushima, Ippei, Akasaka, Takaaki, Morishima, Yoshiyuki, Takita, Atsushi, Motohashi, Tomoko, Kimura, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291522/
https://www.ncbi.nlm.nih.gov/pubmed/32536828
http://dx.doi.org/10.1186/s12959-020-00223-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291522/
https://www.ncbi.nlm.nih.gov/pubmed/32536828
http://dx.doi.org/10.1186/s12959-020-00223-0

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