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Toll-like receptor 9 and the inflammatory response to surgical trauma and cardiopulmonary bypass

OBJECTIVES: Cardiac surgery can lead to post-operative end-organ complications secondary to activation of systemic inflammatory response. We hypothesize that surgical trauma or cardiopulmonary bypass (CPB) may initiate systemic inflammatory response via release of mitochondrial DNA (mtDNA) signaling...

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Detalles Bibliográficos
Autores principales: Naase, Hatam, Harling, Leanne, Kidher, Emaddin, Sepehripour, Amir, Nguyen, Bao, Kapelouzou, Alkistis, Cokkinos, Dennis, Stavridis, George, Angelini, Gianni, Evans, Paul C., Athanasiou, Thanos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291696/
https://www.ncbi.nlm.nih.gov/pubmed/32527277
http://dx.doi.org/10.1186/s13019-020-01179-y