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A novel patient-derived organoids-based xenografts model for preclinical drug response testing in patients with colorectal liver metastases

BACKGROUNDS: Cancer-related mortality in patients with colorectal cancer (CRC) is predominantly caused by development of colorectal liver metastases (CLMs). How to screen the sensitive chemotherapy and targeted therapy is the key element to improve the prognosis of CLMs patients. The study aims to d...

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Detalles Bibliográficos
Autores principales: Jian, Mi, Ren, Li, He, Guodong, Lin, Qi, Tang, Wentao, Chen, Yijiao, Chen, Jingwen, Liu, Tianyu, Ji, Meiling, Wei, Ye, Chang, Wenju, Xu, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291745/
https://www.ncbi.nlm.nih.gov/pubmed/32532289
http://dx.doi.org/10.1186/s12967-020-02407-8