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Ginkgolide-Platinum(II) Complex GPt(II) Exhibits Therapeutic Effect on Depression in Mice via Upregulation of DA and 5-HT Neurotransmitters

BACKGROUND: Depression is the 5(th) most prevalent disorder adversely affecting the health of humans worldwide. The present study evaluated the antidepressant effect of ginkgolide-platinum(II) complex in vivo in a mice model of CMS-induced depression. MATERIAL/METHODS: Depression was induced in mice...

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Detalles Bibliográficos
Autores principales: Yang, Tao, Wang, Xubo, Liu, Lei, Chen, Hanwen, Wang, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291786/
https://www.ncbi.nlm.nih.gov/pubmed/32484164
http://dx.doi.org/10.12659/MSM.922052