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Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase

The spreading of new viruses is known to provoke global human health threat. The current COVID-19 pandemic caused by the recently emerged coronavirus SARS-CoV-2 is one significant and unfortunate example of what the world will have to face in the future with emerging viruses in absence of appropriat...

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Detalles Bibliográficos
Autores principales: Ahmed-Belkacem, Rostom, Sutto-Ortiz, Priscila, Guiraud, Mathis, Canard, Bruno, Vasseur, Jean-Jacques, Decroly, Etienne, Debart, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291971/
https://www.ncbi.nlm.nih.gov/pubmed/32563813
http://dx.doi.org/10.1016/j.ejmech.2020.112557