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Immediate effects of systemic administration of normal and high O(2)-affinity haemoglobin vesicles as a transfusion alternative in a rat pneumonectomy model

BACKGROUND: Haemoglobin vesicles (HbVs) are red blood cell (RBC) substitutes with a phospholipid bilayer membrane and a polyethylene modified surface (diameter=250 nm; P(50)=28 Torr). They can be preserved for years and can be used in patients of all blood types without the risk of infection. Their...

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Detalles Bibliográficos
Autores principales: Hashimoto, Ryo, Kohno, Mitsutomo, Oiwa, Kana, Onozawa, Hiroto, Watanabe, Masazumi, Horinouchi, Hirohisa, Sakai, Hiromi, Kobayashi, Koichi, Iwazaki, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292042/
https://www.ncbi.nlm.nih.gov/pubmed/32527871
http://dx.doi.org/10.1136/bmjresp-2019-000476