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Delayed nivolumab‐induced hepatotoxicity during pazopanib treatment for metastatic renal cell carcinoma: An autopsy case

INTRODUCTION: Pazopanib, a tyrosine kinase inhibitor, and nivolumab, an immune checkpoint inhibitor, are both considered to cause hepatotoxicity with different pathophysiology. We report a case in which a patient died of severe hepatotoxicity who was presumed to have been caused by the administratio...

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Detalles Bibliográficos
Autores principales: Todo, Maki, Kondo, Hideyuki, Hayashi, Taiki, Masuda, Tsukasa, Okabe, Takashi, Kaneko, Go, Oyama, Masafumi, Shirotake, Suguru, Nishimoto, Koshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292132/
https://www.ncbi.nlm.nih.gov/pubmed/32743435
http://dx.doi.org/10.1002/iju5.12101