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Absence of miRNA-146a Differentially Alters Microglia Function and Proteome

Background: MiR-146a is an important regulator of innate inflammatory responses and is also implicated in cell death and survival. Methods: By sorting CNS resident cells, microglia were the main cellular source of miR-146a. Therefore, we investigated microglia function and phenotype in miR-146a knoc...

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Detalles Bibliográficos
Autores principales: Martin, Nellie A., Hyrlov, Kirsten H., Elkjaer, Maria L., Thygesen, Eva K., Wlodarczyk, Agnieszka, Elbaek, Kirstine J., Aboo, Christopher, Okarmus, Justyna, Benedikz, Eirikur, Reynolds, Richard, Hegedus, Zoltan, Stensballe, Allan, Svenningsen, Åsa Fex, Owens, Trevor, Illes, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292149/
https://www.ncbi.nlm.nih.gov/pubmed/32582192
http://dx.doi.org/10.3389/fimmu.2020.01110