Antidepressant amitriptyline‐induced matrix metalloproteinase‐9 activation is mediated by Src family tyrosine kinase, which leads to glial cell line‐derived neurotrophic factor mRNA expression in rat astroglial cells

BACKGROUND: Astrocytes have been implicated in the pathophysiology of mood disorders and in the mechanism of the pharmacological effects of antidepressant drugs by the production of neurotrophic/growth factors. Previous studies have identified astrocyte‐expressed Gα(i/o)‐coupled lysophosphatidic aci...

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Detalles Bibliográficos
Autores principales: Abe, Hiromi, Kajitani, Naoto, Okada‐Tsuchioka, Mami, Omori, Wataru, Yatsumoto, Masahide, Takebayashi, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292280/
https://www.ncbi.nlm.nih.gov/pubmed/31025529
http://dx.doi.org/10.1002/npr2.12055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292280/
https://www.ncbi.nlm.nih.gov/pubmed/31025529
http://dx.doi.org/10.1002/npr2.12055

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