Comprehensive behavioral analysis of indoleamine 2,3‐dioxygenase knockout mice

AIM: Indoleamine 2,3‐dioxygenase 1 (IDO1) metabolizes the essential amino acid tryptophan into kynurenine derivatives, which are involved in neural activity via the kynurenine pathway (KP). IDO1 is an initial rate‐limiting enzyme in the KP and is activated by stress and/or inflammation. The perturba...

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Detalles Bibliográficos
Autores principales: Hirata, Nao, Hattori, Satoko, Shoji, Hirotaka, Funakoshi, Hiroshi, Miyakawa, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292290/
https://www.ncbi.nlm.nih.gov/pubmed/30175526
http://dx.doi.org/10.1002/npr2.12019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292290/
https://www.ncbi.nlm.nih.gov/pubmed/30175526
http://dx.doi.org/10.1002/npr2.12019

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