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Transcriptomic evidence for immaturity induced by antidepressant fluoxetine in the hippocampus and prefrontal cortex

AIMS: The molecular and cellular mechanisms underlying the antidepressant effects of fluoxetine in the brain are not fully understood. Emerging evidence has led to the hypothesis that chronic fluoxetine treatment induces dematuration of certain types of mature neurons in rodents. These studies have...

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Detalles Bibliográficos
Autores principales: Hagihara, Hideo, Ohira, Koji, Miyakawa, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292305/
https://www.ncbi.nlm.nih.gov/pubmed/30772953
http://dx.doi.org/10.1002/npr2.12048