Brexpiprazole has a low risk of dopamine D(2) receptor sensitization and inhibits rebound phenomena related to D(2) and serotonin 5‐HT(2A) receptors in rats

BACKGROUND: Long‐term antipsychotic treatment in patients with schizophrenia can induce supersensitivity psychosis and tardive dyskinesia which is thought to be caused by dopamine D(2) receptor sensitization. We evaluated the effects of brexpiprazole on D(2) receptor sensitivity after subchronic tre...

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Detalles Bibliográficos
Autores principales: Amada, Naoki, Akazawa, Hitomi, Ohgi, Yuta, Maeda, Kenji, Sugino, Haruhiko, Kurahashi, Nobuyuki, Kikuchi, Tetsuro, Futamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292306/
https://www.ncbi.nlm.nih.gov/pubmed/31487433
http://dx.doi.org/10.1002/npr2.12076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292306/
https://www.ncbi.nlm.nih.gov/pubmed/31487433
http://dx.doi.org/10.1002/npr2.12076

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