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Comprehensive behavioral analysis of heterozygous Syngap1 knockout mice

AIMS: Synaptic Ras GTPase‐activating protein 1 (SYNGAP1) regulates synaptic plasticity through AMPA receptor trafficking. SYNGAP1 mutations have been found in human patients with intellectual disability (ID) and autism spectrum disorder (ASD). Almost every individual with SYNGAP1‐related ID develops...

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Detalles Bibliográficos
Autores principales: Nakajima, Ryuichi, Takao, Keizo, Hattori, Satoko, Shoji, Hirotaka, Komiyama, Noboru H., Grant, Seth G. N., Miyakawa, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292322/
https://www.ncbi.nlm.nih.gov/pubmed/31323176
http://dx.doi.org/10.1002/npr2.12073