Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase‐2

AIM: Tryptophan hydroxylase 2 (Tph2) is a rate‐limiting enzyme for the biosynthesis of 5‐hydroxytryptamine (5‐HT, serotonin). Previous studies have reported that C1473G polymorphism of the murine Tph2 gene leads to decreased 5‐HT levels in the brain and abnormal behavioral phenotypes, such as impair...

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Detalles Bibliográficos
Autores principales: Koshimizu, Hisatsugu, Hirata, Nao, Takao, Keizo, Toyama, Keiko, Ichinose, Takashi, Furuya, Shigeki, Miyakawa, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Micro Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292325/
https://www.ncbi.nlm.nih.gov/pubmed/30472790
http://dx.doi.org/10.1002/npr2.12041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292325/
https://www.ncbi.nlm.nih.gov/pubmed/30472790
http://dx.doi.org/10.1002/npr2.12041

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