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Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

BACKGROUND: De novo lipogenesis (DNL) is the primary metabolic pathway synthesizing fatty acids from carbohydrates, protein, or alcohol. Our aim was to examine associations of in vivo levels of selected fatty acids (16:0, 16:1n7, 18:0, 18:1n9) in DNL with incidence of type 2 diabetes (T2D). METHODS...

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Detalles Bibliográficos
Autores principales: Imamura, Fumiaki, Fretts, Amanda M., Marklund, Matti, Ardisson Korat, Andres V., Yang, Wei-Sin, Lankinen, Maria, Qureshi, Waqas, Helmer, Catherine, Chen, Tzu-An, Virtanen, Jyrki K., Wong, Kerry, Bassett, Julie K., Murphy, Rachel, Tintle, Nathan, Yu, Chaoyu Ian, Brouwer, Ingeborg A., Chien, Kuo-Liong, Chen, Yun-yu, Wood, Alexis C., del Gobbo, Liana C., Djousse, Luc, Geleijnse, Johanna M., Giles, Graham G., de Goede, Janette, Gudnason, Vilmundur, Harris, William S., Hodge, Allison, Hu, Frank, Koulman, Albert, Laakso, Markku, Lind, Lars, Lin, Hung-Ju, McKnight, Barbara, Rajaobelina, Kalina, Riserus, Ulf, Robinson, Jennifer G., Samieri, Cecilia, Senn, Mackenzie, Siscovick, David S., Soedamah-Muthu, Sabita S., Sotoodehnia, Nona, Sun, Qi, Tsai, Michael Y., Tuomainen, Tomi-Pekka, Uusitupa, Matti, Wagenknecht, Lynne E., Wareham, Nick J., Wu, Jason H. Y., Micha, Renata, Lemaitre, Rozenn N., Mozaffarian, Dariush, Forouhi, Nita G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292352/
https://www.ncbi.nlm.nih.gov/pubmed/32530938
http://dx.doi.org/10.1371/journal.pmed.1003102