Cargando…

Functions and Clinical Significance of UPF3a Expression in Human Colorectal Cancer

BACKGROUND: Nonsense-mediated mRNA decay (NMD) can degrade mRNAs with a premature termination codon (PTC), and undegraded mRNAs with PTC mutations can induce a genetic compensation response (GCR) by upregulating its compensatory genes. UPF3a refers to up-frame shift 3A (UPF3a) participating in NMD p...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Xinmin, Huang, Yuji, Xu, Weimin, Xiong, Gongyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292372/
https://www.ncbi.nlm.nih.gov/pubmed/32606924
http://dx.doi.org/10.2147/CMAR.S244486