Dietary flavonoid fisetin binds human SUMO1 and blocks sumoylation of p53

Flavonoids are plant-derived compounds that occur abundantly in fruits and vegetables and have been shown to possess potent anti-cancer, antioxidant, and anti-inflammatory properties. However, their direct targets and molecular mechanism of action are not well characterized, hampering exploitation o...

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Detalles Bibliográficos
Autores principales: Velazhahan, Vaithish, Glaza, Przemyslaw, Herrera, Alvaro I., Prakash, Om, Zolkiewski, Michal, Geisbrecht, Brian V., Schrick, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292393/
https://www.ncbi.nlm.nih.gov/pubmed/32530958
http://dx.doi.org/10.1371/journal.pone.0234468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292393/
https://www.ncbi.nlm.nih.gov/pubmed/32530958
http://dx.doi.org/10.1371/journal.pone.0234468

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