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Dietary flavonoid fisetin binds human SUMO1 and blocks sumoylation of p53
Flavonoids are plant-derived compounds that occur abundantly in fruits and vegetables and have been shown to possess potent anti-cancer, antioxidant, and anti-inflammatory properties. However, their direct targets and molecular mechanism of action are not well characterized, hampering exploitation o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292393/ https://www.ncbi.nlm.nih.gov/pubmed/32530958 http://dx.doi.org/10.1371/journal.pone.0234468 |