Self-assembled cGAMP-STINGΔTM signaling complex as a bioinspired platform for cGAMP delivery
The stimulator of interferon (IFN) genes (STING) pathway constitutes a highly important part of immune responses against various cancers and infections. Consequently, administration of STING agonists such as cyclic GMP-AMP (cGAMP) has been identified as a promising approach to target these diseases....
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292616/ https://www.ncbi.nlm.nih.gov/pubmed/32582856 http://dx.doi.org/10.1126/sciadv.aba7589 |