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Skeletal muscle antagonizes antiviral CD8(+) T cell exhaustion
CD8(+) T cells become functionally impaired or “exhausted” in chronic infections, accompanied by unwanted body weight reduction and muscle mass loss. Whether muscle regulates T cell exhaustion remains incompletely understood. We report that mouse skeletal muscle increased interleukin (IL)–15 product...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292629/ https://www.ncbi.nlm.nih.gov/pubmed/32582853 http://dx.doi.org/10.1126/sciadv.aba3458 |