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Skeletal muscle antagonizes antiviral CD8(+) T cell exhaustion

CD8(+) T cells become functionally impaired or “exhausted” in chronic infections, accompanied by unwanted body weight reduction and muscle mass loss. Whether muscle regulates T cell exhaustion remains incompletely understood. We report that mouse skeletal muscle increased interleukin (IL)–15 product...

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Detalles Bibliográficos
Autores principales:	Wu, Jingxia, Weisshaar, Nina, Hotz-Wagenblatt, Agnes, Madi, Alaa, Ma, Sicong, Mieg, Alessa, Hering, Marvin, Mohr, Kerstin, Schlimbach, Tilo, Borgers, Helena, Cui, Guoliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292629/ https://www.ncbi.nlm.nih.gov/pubmed/32582853 http://dx.doi.org/10.1126/sciadv.aba3458

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