The architecture of EMC reveals a path for membrane protein insertion

Approximately 25% of eukaryotic genes code for integral membrane proteins that are assembled at the endoplasmic reticulum. An abundant and widely conserved multi-protein complex termed EMC has been implicated in membrane protein biogenesis, but its mechanism of action is poorly understood. Here, we...

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Detalles Bibliográficos
Autores principales: O'Donnell, John P, Phillips, Ben P, Yagita, Yuichi, Juszkiewicz, Szymon, Wagner, Armin, Malinverni, Duccio, Keenan, Robert J, Miller, Elizabeth A, Hegde, Ramanujan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292650/
https://www.ncbi.nlm.nih.gov/pubmed/32459176
http://dx.doi.org/10.7554/eLife.57887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292650/
https://www.ncbi.nlm.nih.gov/pubmed/32459176
http://dx.doi.org/10.7554/eLife.57887

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