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COVID‐19 hypothesis: Activated protein C for therapy of virus‐induced pathologic thromboinflammation

Seriously ill patients with coronavirus disease 2019 (COVID‐19) at risk for death exhibit elevated cytokine and chemokine levels and D‐dimer, and they often have comorbidities related to vascular dysfunctions. In preclinical studies, activated protein C (APC) provides negative feedback downregulatio...

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Detalles Bibliográficos
Autores principales: Griffin, John H., Lyden, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292662/
https://www.ncbi.nlm.nih.gov/pubmed/32548551
http://dx.doi.org/10.1002/rth2.12362