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FZD10 regulates cell proliferation and mediates Wnt1 induced neurogenesis in the developing spinal cord
Wnt/FZD signalling activity is required for spinal cord development, including the dorsal-ventral patterning of the neural tube, where it affects proliferation and specification of neurons. Wnt ligands initiate canonical, β -catenin-dependent, signaling by binding to Frizzled receptors. However, in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292682/ https://www.ncbi.nlm.nih.gov/pubmed/32531778 http://dx.doi.org/10.1371/journal.pone.0219721 |