Splice-specific deficiency of the PTSD-associated gene PAC1 leads to a paradoxical age-dependent stress behavior

The pituitary adenylate cyclase-activating polypeptide receptor (PAC1, also known as ADCYAP1R1) is associated with post-traumatic stress disorder and modulation of stress response in general. Alternative splicing of PAC1 results in multiple gene products, which differ in their mode of signalling and...

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Detalles Bibliográficos
Autores principales: Biran, Jakob, Gliksberg, Michael, Shirat, Ido, Swaminathan, Amrutha, Levitas-Djerbi, Talia, Appelbaum, Lior, Levkowitz, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292827/
https://www.ncbi.nlm.nih.gov/pubmed/32533011
http://dx.doi.org/10.1038/s41598-020-66447-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292827/
https://www.ncbi.nlm.nih.gov/pubmed/32533011
http://dx.doi.org/10.1038/s41598-020-66447-2

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