Formulation and optimization of liquisolid compact for enhancing dissolution properties of efavirenz by using DoE approach

Efavirenz displays low and variable bioavailability because of its poor aqueous solubility and high log P-value. The present investigation was aimed to improve the dissolution profile of efavirenz by using a simple, scalable and cost-effective technique of liquisolid compact. The drug was dissolved...

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Detalles Bibliográficos
Autores principales: Jaydip, Bhola, Dhaval, Mori, Soniwala, M.M., Chavda, Jayant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292870/
https://www.ncbi.nlm.nih.gov/pubmed/32550806
http://dx.doi.org/10.1016/j.jsps.2020.04.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292870/
https://www.ncbi.nlm.nih.gov/pubmed/32550806
http://dx.doi.org/10.1016/j.jsps.2020.04.016

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