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Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca(2+)-channel
The bronchodilator effects of Roflumilast “a selective phosphodiesterase type-4 (PDE4)” inhibitor studied in this experimental protocol. The spiral strips of isolated guinea-pig tracheal chains mounted in organ bath and maintained in Krebs solution ventilated with carbogen at 32 °C and in Ca(++) res...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292871/ https://www.ncbi.nlm.nih.gov/pubmed/32550801 http://dx.doi.org/10.1016/j.jsps.2020.04.011 |