Cargando…

Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca(2+)-channel

The bronchodilator effects of Roflumilast “a selective phosphodiesterase type-4 (PDE4)” inhibitor studied in this experimental protocol. The spiral strips of isolated guinea-pig tracheal chains mounted in organ bath and maintained in Krebs solution ventilated with carbogen at 32 °C and in Ca(++) res...

Descripción completa

Detalles Bibliográficos
Autores principales: Imam, Faisal, Rehman, Najeeb Ur, Ansari, Mohd Nazam, Qamar, Wajhul, Afzal, Muhammad, Alharbi, Khalid Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292871/
https://www.ncbi.nlm.nih.gov/pubmed/32550801
http://dx.doi.org/10.1016/j.jsps.2020.04.011