Intra-tumoral drug concentration mapping within solid tumor micro-milieu using in-vitro model and doxorubicin as a model drug

In contrast to plasma pharmacokinetics, intratumoral pharmacokinetics of doxorubicin (DOX) determines its spatial anti-tumoral activity. Three-dimensional multicellular layers (MCL) model for solid tumors present optimum experimental platform for studying the intratumoral pharmacokinetics of DOX. Th...

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Detalles Bibliográficos
Autores principales: Al-Abd, Ahmed M., Khedr, Alaa, Atteiah, Salah G., Al-Abbasi, Fahad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292875/
https://www.ncbi.nlm.nih.gov/pubmed/32550808
http://dx.doi.org/10.1016/j.jsps.2020.05.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292875/
https://www.ncbi.nlm.nih.gov/pubmed/32550808
http://dx.doi.org/10.1016/j.jsps.2020.05.001

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