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Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma

Airway smooth muscle (ASM) plays a major role in acute airway narrowing and reducing ASM thickness is expected to attenuate airway hyper‐responsiveness and disease burden. There are two therapeutic approaches to reduce ASM thickness: (a) a direct approach, targeting specific airways, best exemplifie...

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Detalles Bibliográficos
Autores principales: Donovan, Graham M., Wang, Kimberley C. W., Shamsuddin, Danial, Mann, Tracy S., Henry, Peter J., Larcombe, Alexander N., Noble, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292900/
https://www.ncbi.nlm.nih.gov/pubmed/32533641
http://dx.doi.org/10.14814/phy2.14451