Integrating NMR and simulations reveals motions in the UUCG tetraloop

We provide an atomic-level description of the structure and dynamics of the UUCG RNA stem–loop by combining molecular dynamics simulations with experimental data. The integration of simulations with exact nuclear Overhauser enhancements data allowed us to characterize two distinct states of this mol...

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Detalles Bibliográficos
Autores principales: Bottaro, Sandro, Nichols, Parker J, Vögeli, Beat, Parrinello, Michele, Lindorff-Larsen, Kresten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293013/
https://www.ncbi.nlm.nih.gov/pubmed/32427326
http://dx.doi.org/10.1093/nar/gkaa399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293013/
https://www.ncbi.nlm.nih.gov/pubmed/32427326
http://dx.doi.org/10.1093/nar/gkaa399

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