Cargando…

The geometric influence on the Cys(2)His(2) zinc finger domain and functional plasticity

The Cys(2)His(2) zinc finger is the most common DNA-binding domain expanding in metazoans since the fungi human split. A proposed catalyst for this expansion is an arms race to silence transposable elements yet it remains poorly understood how this domain is able to evolve the required specificities...

Descripción completa

Detalles Bibliográficos
Autores principales: Mueller, April L, Corbi-Verge, Carles, Giganti, David O, Ichikawa, David M, Spencer, Jeffrey M, MacRae, Mark, Garton, Michael, Kim, Philip M, Noyes, Marcus B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293014/
https://www.ncbi.nlm.nih.gov/pubmed/32383734
http://dx.doi.org/10.1093/nar/gkaa291