Structural basis of the XPB–Bax1 complex as a dynamic helicase–nuclease machinery for DNA repair

Nucleotide excision repair (NER) is a major DNA repair pathway for a variety of DNA lesions. XPB plays a key role in DNA opening at damage sites and coordinating damage incision by nucleases. XPB is conserved from archaea to human. In archaea, XPB is associated with a nuclease Bax1. Here we report c...

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Detalles Bibliográficos
Autores principales: DuPrez, Kevin, He, Feng, Chen, Zhenhang, Hilario, Eduardo, Fan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293015/
https://www.ncbi.nlm.nih.gov/pubmed/32374860
http://dx.doi.org/10.1093/nar/gkaa324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293015/
https://www.ncbi.nlm.nih.gov/pubmed/32374860
http://dx.doi.org/10.1093/nar/gkaa324

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