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Structural basis of the XPB–Bax1 complex as a dynamic helicase–nuclease machinery for DNA repair
Nucleotide excision repair (NER) is a major DNA repair pathway for a variety of DNA lesions. XPB plays a key role in DNA opening at damage sites and coordinating damage incision by nucleases. XPB is conserved from archaea to human. In archaea, XPB is associated with a nuclease Bax1. Here we report c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293015/ https://www.ncbi.nlm.nih.gov/pubmed/32374860 http://dx.doi.org/10.1093/nar/gkaa324 |