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Protamine loops DNA in multiple steps

Protamine proteins dramatically condense DNA in sperm to almost crystalline packing levels. Here, we measure the first step in the in vitro pathway, the folding of DNA into a single loop. Current models for DNA loop formation are one-step, all-or-nothing models with a looped state and an unlooped st...

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Detalles Bibliográficos
Autores principales: Ukogu, Obinna A, Smith, Adam D, Devenica, Luka M, Bediako, Hilary, McMillan, Ryan B, Ma, Yuxing, Balaji, Ashwin, Schwab, Robert D, Anwar, Shahzad, Dasgupta, Moumita, Carter, Ashley R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293030/
https://www.ncbi.nlm.nih.gov/pubmed/32392345
http://dx.doi.org/10.1093/nar/gkaa365